BALTIMORE, MD (ASRN.ORG)- One cell...one initial set of genetic changes - that's all it takes to begin a series of events that lead to metastatic cancer.  Now, Johns Hopkins experts have tracked how the cancer process began in 33 men with prostate cancer who died of the disease.  Culling information from autopsies, their study points to a set of genetic defects in a single cell that are different for each person's cancer.

"These were not your average autopsies," says pathologist G. Steven Bova, M.D., assistant professor of pathology at Johns Hopkins.  "We dissected every bit of tumor - in the primary and met